Methylation Support IV bag, compounded at Nature & Science Medicine

Nutrient IVs · Encinitas, CA

Methylation Support IV

Support your methylation with activated B12 (methylcobalamin) and folinic acid.

Starting at$225

Sizes and prices

  • Small · 250ml$225
  • Medium · 500ml$285
  • Large · 1000ml$395
Book this IV — from $225
Not sure this is the right one for you?
Book an IV consultation Call (858) 800-2555
Meet the team behind your IV

What this one is

For when your methylation cycle needs help running. We use folinic acid — folate that's already converted, so it doesn't depend on the conversion step that varies from person to person — plus a raised dose of methylcobalamin B12 by injection. Together they're the pair that reliably brings homocysteine down. Methionine and choline supply the methyl donors.

How this one differs from our base Nutrient IV

  • Folinic Acid added — as Leucovorin Calcium, an active form of folate
  • 4× the methylcobalamin, the active form of B12
  • Double the NAC

Every ingredient, every dose

IngredientSmall250mlMedium500mlLarge1000ml
Magnesiumas magnesium chloride200 mg400 mg600 mg
Vitamin Cascorbic acid500 mg1 g1.5 g
Vitamin B12methylcobalamin — the active form2.5–5 mg5–10 mg5–10 mg
Vitamin B650 mg50 mg100 mg
B-ComplexB1 shown — also contains B2, B3, B5 and B625 mg50 mg100 mg
Vitamin B5dexpanthenol125 mg250 mg250 mg
MIC + Carnitinemethionine, inositol, choline and carnitine combined87.5 mg175 mg175 mg
Taurineamino acid25 mg50 mg100 mg
NACN-acetylcysteine50 mg100 mg100 mg
Folateas folinic acid5 mg10 mg20 mg
Glycineamino acid25 mg50 mg50 mg

Swipe the table sideways to see all 3 sizes.

Want the science? Every ingredient in this bag, with the peer-reviewed studies behind it. Read the research
Why we publish this

We post every formula because we know ours are the best.

Dosing an IV properly costs more to make. The two usual ways out are to charge double or to put less in the bag — we do neither, and take the smaller margin instead.

So every ingredient and every dose is on this page, at every size. Read ours, then go and try to read anyone else’s.

The other formulas

Every one published in full, the same way.

Methylation Support IV questions

Prices checked October 2026.

How much does a Methylation Support IV cost?
At Nature & Science Medicine in Encinitas, CA, the Methylation Support IV starts at $225. Sizes and prices: Small, 250ml: $225; Medium, 500ml: $285; Large, 1000ml: $395. The price on this page is the price at the desk, with no membership. New patients get a complimentary consultation with a licensed naturopathic doctor.
What is in your Methylation Support IV?
Our Methylation Support IV contains Magnesium (200 mg to 600 mg), Vitamin C (500 mg to 1.5 g), Vitamin B12 (2.5–5 mg to 5–10 mg), Vitamin B6 (50 mg to 100 mg), B-Complex (25 mg to 100 mg), Vitamin B5 (125 mg to 250 mg), MIC + Carnitine (87.5 mg to 175 mg), Taurine (25 mg to 100 mg), NAC (50 mg to 100 mg), Folate (5 mg to 20 mg) and Glycine (25 mg to 50 mg), depending on the size. Every ingredient and dose is published on this page, down to the milligram. The formula was designed by our naturopathic doctors, Dr. Nikodemas McNulty, ND and Dr. Erin Biller, ND.
Where can I get a Methylation Support IV near Encinitas?
At Nature & Science Medicine, 531 Encinitas Blvd, Suite 121, Encinitas, CA 92024, with free parking on site. We are open 10am to 5pm, seven days a week, an easy drive from Carlsbad, Solana Beach, Del Mar and Rancho Santa Fe. Book online from this page, or call or text (858) 800-2555.

Read the formula. Then come and get it.

Every dose on this page is published because you should be able to read exactly what we would put in you before you agree to it.

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Open 10am–5pm, 7 days a week · 531 Encinitas Blvd, Suite 121 · Free parking