Methylation Support IV bag, compounded at Nature & Science Medicine

Nutrient IVs

Methylation Support IV

Support your methylation with activated B12 (methylcobalamin) and folinic acid.

Starting at$225

Sizes and prices

  • Small · 250ml$225
  • Medium · 500ml$285
  • Large · 1000ml$395
Not sure this is the right one for you?

What this one is

For when your methylation cycle needs help running. We use folinic acid — folate that's already converted, so it doesn't depend on the conversion step that varies from person to person — plus a raised dose of methylcobalamin B12 by injection. Together they're the pair that reliably brings homocysteine down. Methionine and choline supply the methyl donors.

How this one differs from our base Nutrient IV

  • Folinic Acid added — as Leucovorin Calcium, an active form of folate
  • 4× the methylcobalamin, the active form of B12
  • Double the NAC

Every ingredient, every dose

IngredientSmall250mlMedium500mlLarge1000ml
Magnesiumas magnesium chloride200 mg400 mg600 mg
Vitamin Cascorbic acid500 mg1 g1.5 g
Vitamin B12methylcobalamin — the active form2.5–5 mg5–10 mg5–10 mg
Vitamin B650 mg50 mg100 mg
B-ComplexB1 shown — also contains B2, B3, B5 and B625 mg50 mg100 mg
Vitamin B5dexpanthenol125 mg250 mg250 mg
MIC + Carnitinemethionine, inositol, choline and carnitine combined87.5 mg175 mg175 mg
Taurineamino acid25 mg50 mg100 mg
NACN-acetylcysteine50 mg100 mg100 mg
Folateas folinic acid5 mg10 mg20 mg
Glycineamino acid50 mg50 mg

Swipe the table sideways to see all 3 sizes.

Want the science? Every ingredient in this bag, with the peer-reviewed studies behind it. Read the research
Why we publish this

We post every formula because we know ours are the best.

Dosing an IV properly costs more to make. The two usual ways out are to charge double or to put less in the bag — we do neither, and take the smaller margin instead.

So every ingredient and every dose is on this page, at every size. Read ours, then go and try to read anyone else’s.

Read the formula. Then come and get it.

Every dose on this page is published because you should be able to read exactly what we would put in you before you agree to it.

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